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We have identified trimetazidine as a candidate to treat bipolar depression [19] using an in silico treatment discovery model in diabetes [18] that led to a successful Phase 2 clinical trial to treat diabetes [115]

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The mortality rate increased with age and was significantly greater in those older than 65-years-old with comorbidities

Recent evidence suggests that NF-B plays a critical role in the early events controlling the molecular response to ROS [54, 55, 58, 103]